For a youthful, firmer you, ask for Sculptra®
Sculptra® stimulates your skin’s own natural collagen and elastin production.1–4 With Sculptra®, you will renew skin thickness and firmness and correct shallow to deep wrinkles and folds.5-9
Sculptra® gradually builds your skin’s structural foundations for radiant, natural-looking, rejuvenated skin.5,8-10

Sculptra® as a collagen biostimulator
Sculptra® is a regenerative biostimulator that stimulates your skin’s ability to produce collagen and elastin, rebuilding your skin’s structure and increasing its natural firmness.1–4, 8-10
Collagen is a fibrous protein in the deeper layers of your skin and is key for youthful-looking skin.11 As you age, your body’s collagen production decreases. The loss of collagen will in time lead to loose and saggy skin, such as jowls, and the formation of facial wrinkles and folds.11
Find out more about collagen, including what it is and what it does for your face and skin.
Sculptra® is the first proven regenerative biostimulator injectable that will renew your skin in a progressive way with natural-looking, long-lasting results, showing improvements for up to 2 years.7, 9,12-14
Treatment areas: Sculptra® for jowls, cheeks, and chin
Sculptra® can help to add volume and firmness to areas of your face that have become loose and saggy.8-11 These treatment areas include jowls, cheeks, smile lines (nasolabial folds), laugh lines (marionette lines), and chin wrinkles.15 Sculptra® regenerative biostimulator treatments help to stimulate collagen and elastin in your skin.3,4
Sculptra® for cheeks
As you age, your skin loses volume, which can result in sunken cheeks. This can be due to a loss of facial fullness, and bone resorption that comes with age.16-18 Because of this, people often seek out collagen treatments to help add volume to their cheeks. Regenerative biostimulator injections, like Sculptra®, help to stimulate your own collagen and elastin production contributing to a more youthful look.3-5,9
Sculptra® for jowls and chin
Your skin also loses some of its elasticity as you age, which alongside bone resorption, moving fat pads, and loss of volume higher up in the face, can result in a sagging jawline.15–17 Sculptra® can help stimulate your body’s own collagen and elastin production in your face, helping to gradually rebuild your skin’s structural foundation.3-5, 10
Sculptra® for wrinkles, deep folds, and lines
Wrinkles on the face also come with aging, as changes to collagen, fat, and bone take place.16-18 Wrinkles and folds, such as deep folds between the nose and mouth (nasolabial folds), and lines framing the mouth (marionette lines) can become more pronounced.11 Sculptra® helps to improve skin thickness and increase skin firmness and has been found to help improve the appearance of wrinkles and folds.1–5,8-10



Your Sculptra® treatment
Sculptra® is injected into the deep layers of your skin to stimulate your skin’s own collagen and elastin production.1–4 You will gradually notice visible improvements in skin firmness and fullness.5,8,9
Immediately after each treatment session, you may experience some swelling that will temporarily reduce wrinkles and folds. Thereafter, the gradual process of collagen replacement starts. Sculptra® works subtly, improving facial areas gradually to give you a youthful and natural-looking result that lasts.
How long does a Sculptra® regenerative biostimulator last?
Sculptra® will reinvigorate your skin and bring back your youthful appearance. Results may last for more than two years.7,9,13
In a clinical study, 80% of users were still satisfied with their Sculptra® collagen regenerative biostimulator treatment 25 months after their last injection.19

How does Sculptra® work to stimulate collagen?
The active ingredient of Sculptra® is a poly-L-Lactic acid, PLLA-SCATM. PLLA-SCATM is a biodegradable substance that has been used for decades in dissolvable stitches for wound management.15,20 When PLLA-SCATM is injected into the deeper layers of your skin, it helps stimulate your skin’s own natural collagen and elastin production.1–4
This results in your skin’s inner structure being improved, and you will regain skin volume that has been lost due to aging.
Sculptra® before and after
View pictures of before and after a Sculptra® treatment. See the differences in hollow cheeks, chin wrinkles, smile and laugh lines, and jowls before and after Sculptra®.

80%
rated Sculptra® as good to excellent after 25 months19
100%
of patients would recommend Sculptra® to a friend5
First approved in Europe in
1999 21,22
Frequently asked questions about Sculptra®
Is Scupltra® a collagen injection?
No, Sculptra®is not a collagen injection, it is the first proven regenerative biostimulator made of poly-L-Lactic acid (PLLA-SCATM), Sculptra® stimulates collagen and elastin production.1–4 Collagen biostimulators have been found to have longer-lasting results than collagen injections.13
What is the difference between collagen injections and a collagen biostimulator injectable?
A collagen injection is an injection of collagen into the skin. Whereas a collagen regenerative biostimulator is an injection of poly-L-Lactic acid that stimulates your body to create its own collagen.
Sculptra®, as a regenerative biostimulator, was compared to human-derived collagen injections for treating nasolabial fold wrinkles. Results showed that Sculptra® maintained over 86% improvement at 25 months, while human-derived collagen dropped from 94% improvement at three weeks to just 6% at 13 months.13
How long does a Sculptra® collagen regenerative biostimulator treatment last?
A Sculptra® collagen regenerative biostimulator treatment has long-lasting results. Clinical trials show that improvements last around 2 years.7,9,13
How should I prepare before my consultation?
Before your first Sculptra® treatment, you will have a consultation. Think through what you want to achieve and any questions you want to ask your healthcare practitioner. You will be informed about how Sculptra® works and how it can be used safely to improve your skin’s firmness.
Your healthcare practitioner will also ask you about your medical history. After the consultation, you should feel well-informed about Sculptra® and know what results to expect.
What should I think about when choosing a clinic?
Make sure that the clinic has a qualified practitioner(s) so that your treatment will be performed correctly. You may also search in national registers of licensed aesthetic treatment specialists. Your treatment should be performed in a medical environment that provides privacy and is clean. You can always request to see training certificates and insurance certificates to ensure that your healthcare practitioner has received the appropriate training and is insured for the treatment.
Who can inject Sculptra®?
Specialists who have been trained to inject Sculptra® and who are licensed to practice within your country or state may administer the treatment. This can include physician assistants, nurse practitioners, registered nurses, and other trained personnel.
Are you looking for a clinic?
Skin insights
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References
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- US Patent 7731758 B2 (v1.0).
- Sculptra IFU.
- Haddad Aet al. J Drugs Dermatol. 2019;18(9):929-935.
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- Brown SA et al. Plast Reconstr Surg. 2011;127(4):1684-1692.
- Chen HL et al. Adv Skin Wound Care. 2023;36(9):1-8.
- Galderma Data on File MA-54151 ISO - 13485 (v1.0).
- FDA Marketing approval Sculptra (v1.0).
- Guarnieri Munia C et al. J Clin Aesthet Dermatol. 2023;16(6):26-29.
- Restylane Eyelight IFU.
- Humphrey CD, Lawrence AC. Facial Plast Surg. 2023 Dec;39(6):719–21.
- Palm M et al. J Drugs Dermatol. 2021;20(7):760-766.
- Galderma Data on File MA-46589 (v1.0).
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