The Galderma aesthetics range, RESTYLANE and Restylane Refyne - to fill lines and wrinkles

To fill lines and wrinkles, try Restylane®.

Restylane® has specialized fillers with lidocaine such as Restylane® Defyne™ and Refyne™ to provide desired shape, contour, and definition. These dermal filler treatments are suitable for the correction of wrinkles and folds while maintaining natural expression. Treatment areas may include marionette lines (laugh lines)1 and nasolabial folds (smile lines)1. Get tailored and natural-looking results you’ll love2.

Why Fill?
The Galderma aesthetics range, Why choose RESTYLANE or Restylane Refyne treatments

Why fill with Restylane®?

Our skin becomes thinner and less elastic as we age, reducing its ability to retain water. The result is the appearance of fine lines and wrinkles, and you may feel that you look tired, old or sad. Treatments with dermal fillers help to restore and maintain a youthful-looking appearance and regain lost confidence3.

Restylane® Classyc™ is a firmer dermal filler treatment that can be used to fill wrinkles where you have good tissue coverage. Restylane® Refyne™ and Restylane® Defyne™ are softer and more flexible dermal filler treatments that can be used to improve the more dynamic areas of your face, such as around the lips, the nasolabial folds and the marionette lines4. Restylane® helps you refine your looks and realize your individual needs and desires.

Treatment areas

Restylane® treatment areas

The Restylane® family of dermal filler treatments can be used to reduce lines and wrinkles and help you achieve a refined and natural look. Treatment areas include fine lines around the mouth and eyes, as well as nasolabial folds and marionette lines.

“And if you then all of a sudden see how signs of aging, signs of tiredness or negative expressions are erased from your face, that’s a very positive experience and usually you can see this when the patient looks in the mirror. Their face starts smiling, and that is a very rewarding moment really for an aesthetic doctor.”

Christoph Martschin, dermatologist, Sweden

The Galderma aesthetics range, RESTYLANE and Restylane Refyne - Treatment areas
TEAR TROUGH
MARIONETTE LINES
NASOLABIAL FOLDS
LIPS
UPPER LIP LINES
The Galderma aesthetics range, RESTYLANE and Restylane Refyne - Treatment areas
LIPS
NASOLABIAL FOLDS
TEAR TROUGH
UPPER LIP LINES
MARIONETTE LINES
Your treatment
The Galderma aesthetics range, RESTYLANE and Restylane Refyne - Your treatment

Your Restylane® treatment

A treatment with Restylane® takes approximately 15-45 minutes, depending on the treatment area. You might need a touch-up treatment after the initial treatment to optimize your results. Restylane® filler treatments contain lidocaine, a local anaesthetic that takes away most of the discomfort during treatment. 

Immediately after your dermal filler treatment, you may experience some post-treatment side effects, such as redness, swelling, pain, bruising or tenderness at the treatment site. These side effects usually disappear within one week after injection. Though fillers are minimally invasive, they still carry some risks. Before the treatment, discuss all possible risks and benefits with your healthcare practitioner. View Important Safety Information.

Restylane® gives you long-lasting but non-permanent results, meaning you can continuously refine your looks. 

How it works
The Galderma aesthetics range, RESTYLANE and Restylane Refyne - The science behind

How it works

Hyaluronic acid is a substance that has a unique ability to bind water. Hyaluronic acid occurs naturally in our bodies and in all layers of our skin. It keeps your body tissues soft, hydrated, and flexible. However, as we age, the body’s ability to produce hyaluronic acid lessens, leading to dry, thinner skin.  

Natural hyaluronic acid in the body degrades quickly, in one to two days. To make the hyaluronic acid in Restylane® Defyne™ and Restylane® Refyne™ last longer — Galderma has used stabilization technologies that delay degradation.

 
Restylane® contains a hyaluronic acid gel with a firmer consistency and Restylane® Refyne™ contains a gel with a more flexible consistency to target different kinds of lines and wrinkles.

Upon its launch in 1996, Restylane® was the first ever non-animal stabilized hyaluronic acid treatment filler. Restylane® has become the gold standard of dermal fillers treatments.

Before & After

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Long-lasting results – with one treatment.7

96%

of patients thought that their results looked natural8

100%

of patients saw improvement in their appearance 1 month after treatment9

Frequently asked questions

Results vary from patient to patient. With a repeated treatment plan, results may be long-lasting. As Restylane® is a non-permanent injectable hyaluronic acid product, the effect gradually diminishes with time. Results may vary depending on the treatment area and individual patient.

A top-up treatment is one or more additional treatment after your initial session to help maintain your results. Talk to your healthcare professional to see if a top-up treatment is right for you, and when and how much Restylane® may be needed.

•    Avoid applying make-up to the skin immediately after treatment.
•    Light cover up may be used to conceal any remaining redness after approximately 24 hours.
•    A yellow-toned concealer may be used to hide signs of bruising.
•    In order to cover up any redness, a concealer with a slight green/yellow tone is recommended.

The most common side effects include treatment site reactions such as swelling, bruising, redness, pain and tenderness. These side effects generally disappear within one week after injection. Other potential side effects can occur with dermal filler injections. You should discuss the potential treatment risks with your healthcare practitioner. View Important Safety Information.

Restylane® is manufactured by Q-Med, a Swedish division of Galderma. Galderma is a pharmaceutical company with over 6,000 employees worldwide. The company specializes in dermatology and is present in more than 100 countries. To read more about Galderma visit About Galderma. 

Skin insights

Galderma aesthetics and Restylane - Aesthetic treatments with dermal fillers have been used for many years.

How to find an aesthetic clinic that you can trust

Our portfolio of products

Galderma has developed a diverse portfolio of products that work together.

The Galderma aesthetics range, Restylane Skinboosters

Refresh

Refresh your skin from within with a boost of hyaluronic acid, for a refreshed and vibrant long-lasting look.

The Galderma aesthetics range, Restylane, Sculptra

Renew

Renew the structure of your skin with a collagen stimulator that gradually builds the foundation of the youthful-looking, firmer you.

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References

  1. Philipp-Dormston WG et al. Dermatol Surg 2018;44(6):826-832.; Weiss RA et al. Dermatol Surg 2016;42:699–709.; Narins RS et al. Dermatol Surg 2011;37:644–650.
  2. Talarico S et al. Dermatol Surg 2015;41:1361–1369.; Rzany B et al. Dermatol Surg 2012;38:1153–1161.
  3. Talarico S et al. Dermatol Surg 2015;41:1361–1369.; Rzany B et al. Dermatol Surg 2012;38:1153–1161.
  4. Philipp-Dormston WG et al. Dermatol Surg 2018;44(6):826-832.
  5. Narins RS et al. Dermatol Surg 2008;34:S2–S8.; Rzany B et al. Dermatol Surg 2017;43:58–65.
  6. Narins RS et al. Dermatol Surg 2008;34:S2–S8.; Rzany B et al. Dermatol Surg 2017;43:58–65.
  7. Rzany B et al. Dermatol Surg 2017;43:58–65.; Narins RS et al. Dermatol Surg 2008;34:S2–S8.
  8. Rzany B et al. Dermatol Surg 2012;38:1153–1161.
  9. Swift A et al. Clin Cosmet Investig Dermatol 2017;10:229–238.